BDBM201630 6-chloro-2-((6-(pyrrolidin-1-yl)pyridin-2-yl)methoxy)-4-(tetrahydro-2h-pyran-4-yloxy)quinazoline::US9540384, 22
SMILES Clc1ccc2nc(OCc3cccc(n3)N3CCCC3)nc(OC3CCCOC3)c2c1
InChI Key InChIKey=ISUVZXDVLGUQPC-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 201630
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataIC50: 94nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 .mu.l contained 20 mM HEPES pH=7.5/10 mM M...More data for this Ligand-Target Pair