BDBM201630 6-chloro-2-((6-(pyrrolidin-1-yl)pyridin-2-yl)methoxy)-4-(tetrahydro-2h-pyran-4-yloxy)quinazoline::US9540384, 22

SMILES Clc1ccc2nc(OCc3cccc(n3)N3CCCC3)nc(OC3CCCOC3)c2c1

InChI Key InChIKey=ISUVZXDVLGUQPC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 201630   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM201630(6-chloro-2-((6-(pyrrolidin-1-yl)pyridin-2-yl)metho...)
Affinity DataIC50:  94nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 .mu.l contained 20 mM HEPES pH=7.5/10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent