BDBM202027 4-(2-(pyridin-3-yl)-6-((6-(pyrrolidin-1-yl)pyridin-2-yl)methoxy)-pyrimidin-4-yl)morpholine::US9540384, 24
SMILES C(Oc1cc(nc(n1)-c1cccnc1)N1CCOCC1)c1cccc(n1)N1CCCC1
InChI Key InChIKey=FUWYZGVFJFLIMF-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 202027
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataIC50: 1.63E+3nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 .mu.l contained 20 mM HEPES pH=7.5/10 mM M...More data for this Ligand-Target Pair