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BDBM202245 US9238619, 8

SMILES: Cn1cc(cn1)S(=O)(=O)NCCOc1cccc(c1)C(CN)Cc1ccc(Cl)cc1

InChI Key: InChIKey=QKQRCZOFDCTJEI-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 202245   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycine transporter 1


(Homo sapiens (Human))
BDBM202245
PNG
(US9238619, 8)
Show SMILES Cn1cc(cn1)S(=O)(=O)NCCOc1cccc(c1)C(CN)Cc1ccc(Cl)cc1
Show InChI InChI=1S/C21H25ClN4O3S/c1-26-15-21(14-24-26)30(27,28)25-9-10-29-20-4-2-3-17(12-20)18(13-23)11-16-5-7-19(22)8-6-16/h2-8,12,14-15,18,25H,9-11,13,23H2,1H3
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
<1n/an/an/an/an/an/an/an/a



AbbVie Deutschland GmbH & Co. KG; AbbVie Inc.

US Patent


Assay Description
Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...


US Patent US9238619 (2016)


BindingDB Entry DOI: 10.7270/Q2XS5T6F
More data for this
Ligand-Target Pair