BDBM202290 US9540357, example 1::US9540357, example 2

SMILES OC(\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O)c1cccc(Br)c1

InChI Key InChIKey=UPYGJDCCMCUPIN-HZGHLMDASA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 202290   

TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM202290(US9540357, example 1 | US9540357, example 2)
Affinity DataKi:  1.21E+3nM ΔG°:  -8.07kcal/molepH: 7.4 T: 2°CAssay Description:A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM202290(US9540357, example 1 | US9540357, example 2)
Affinity DataKi:  2.04E+3nM ΔG°:  -7.76kcal/molepH: 7.4 T: 2°CAssay Description:A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM202290(US9540357, example 1 | US9540357, example 2)
Affinity DataKi:  7.49E+3nM ΔG°:  -6.99kcal/molepH: 7.4 T: 2°CAssay Description:A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM202290(US9540357, example 1 | US9540357, example 2)
Affinity DataKi: >1.00E+4nM ΔG°: >-6.82kcal/molepH: 7.4 T: 2°CAssay Description:A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent