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BDBM202312 US9238619, 48

SMILES: CCOC(=O)N1CC(Cc2ccccc2)(C1)c1cccc(OCCNS(=O)(=O)CC2CC2)c1

InChI Key: InChIKey=PQSAQCVJELMITK-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 202312   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycine transporter 1


(Homo sapiens (Human))
BDBM202312
PNG
(US9238619, 48)
Show SMILES CCOC(=O)N1CC(Cc2ccccc2)(C1)c1cccc(OCCNS(=O)(=O)CC2CC2)c1
Show InChI InChI=1S/C25H32N2O5S/c1-2-31-24(28)27-18-25(19-27,16-20-7-4-3-5-8-20)22-9-6-10-23(15-22)32-14-13-26-33(29,30)17-21-11-12-21/h3-10,15,21,26H,2,11-14,16-19H2,1H3
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
<1n/an/an/an/an/an/an/an/a



AbbVie Deutschland GmbH & Co. KG; AbbVie Inc.

US Patent


Assay Description
Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...


US Patent US9238619 (2016)


BindingDB Entry DOI: 10.7270/Q2XS5T6F
More data for this
Ligand-Target Pair