BDBM202318 US9540357, example 13

SMILES Cc1cc(Cl)ccc1-c1cccc(c1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O

InChI Key InChIKey=WTJGQILWUSNOPS-AUNKXPJZSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 202318   

TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM202318(US9540357, example 13)
Affinity DataKi:  23nM ΔG°:  -10.4kcal/molepH: 7.4 T: 2°CAssay Description:A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM202318(US9540357, example 13)
Affinity DataKi:  4.32E+3nM ΔG°:  -7.31kcal/molepH: 7.4 T: 2°CAssay Description:A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent