BindingDB logo
myBDB logout

BDBM202357 US9238619, 74

SMILES: CN(CCOc1cccc(c1)C1(Cc2ccccc2)CCN(C)C1)S(=O)(=O)c1cn(C)cn1

InChI Key: InChIKey=PKUNQFTZTCBZGM-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 202357   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycine transporter 1


(Homo sapiens (Human))
BDBM202357
PNG
(US9238619, 74)
Show SMILES CN(CCOc1cccc(c1)C1(Cc2ccccc2)CCN(C)C1)S(=O)(=O)c1cn(C)cn1
Show InChI InChI=1S/C25H32N4O3S/c1-27-13-12-25(19-27,17-21-8-5-4-6-9-21)22-10-7-11-23(16-22)32-15-14-29(3)33(30,31)24-18-28(2)20-26-24/h4-11,16,18,20H,12-15,17,19H2,1-3H3
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
<1n/an/an/an/an/an/an/an/a



AbbVie Deutschland GmbH & Co. KG; AbbVie Inc.

US Patent


Assay Description
Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...


US Patent US9238619 (2016)


BindingDB Entry DOI: 10.7270/Q2XS5T6F
More data for this
Ligand-Target Pair