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BDBM202360 US9238619, 77

SMILES: CC(C)N1CCC(Cc2ccccc2)(C1)c1cccc(OCCNS(=O)(=O)c2cn(C)cn2)c1

InChI Key: InChIKey=RJMXPCSRWXTANQ-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 202360   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycine transporter 1


(Homo sapiens (Human))
BDBM202360
PNG
(US9238619, 77)
Show SMILES CC(C)N1CCC(Cc2ccccc2)(C1)c1cccc(OCCNS(=O)(=O)c2cn(C)cn2)c1
Show InChI InChI=1S/C26H34N4O3S/c1-21(2)30-14-12-26(19-30,17-22-8-5-4-6-9-22)23-10-7-11-24(16-23)33-15-13-28-34(31,32)25-18-29(3)20-27-25/h4-11,16,18,20-21,28H,12-15,17,19H2,1-3H3
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
<1n/an/an/an/an/an/an/an/a



AbbVie Deutschland GmbH & Co. KG; AbbVie Inc.

US Patent


Assay Description
Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...


US Patent US9238619 (2016)


BindingDB Entry DOI: 10.7270/Q2XS5T6F
More data for this
Ligand-Target Pair