BDBM202385 US9238629, I-17
SMILES COc1cccc(Nc2ncc(Cl)c(Nc3cccc(NC(=O)C=C)c3)n2)c1OC
InChI Key InChIKey=BHJUAKDTALSDNG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 202385
TargetEpidermal growth factor receptor [1-745,751-967](Homo sapiens (Human))
Celgene Avilomics Research
US Patent
Celgene Avilomics Research
US Patent
Affinity DataEC50: 750nMAssay Description:To assess phosphor-EGFR signaling, blots were probed with rabbit anti-Phospho-EGFR (Y1068) and mouse total anti-EGFR antibodies. Phospho-EGFR signal ...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Celgene Avilomics Research
US Patent
Celgene Avilomics Research
US Patent
Affinity DataIC50: 55nMpH: 7.5 T: 2°CAssay Description:Briefly, 10x stocks of EGFR-WT (PV3872) from Invitrogen and
EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif.,
1.13x ATP (AS001A) and...More data for this Ligand-Target Pair
Affinity DataIC50: 650nMpH: 7.5 T: 2°CAssay Description:Briefly, 10x stocks of EGFR-WT (PV3872) from Invitrogen and
EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif.,
1.13x ATP (AS001A) and...More data for this Ligand-Target Pair