BDBM202460 US9540357, example 32::US9540357, example 33

SMILES Cc1cc(Cl)ccc1-c1ccc(s1)C(O)\C=C\[C@H]1CCC(=O)N1CCCc1ccc(cc1)C(O)=O

InChI Key InChIKey=CHEGULSFMGKALD-RRPJXJBHSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 202460   

TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM202460(US9540357, example 32 | US9540357, example 33)
Affinity DataKi:  536nM ΔG°:  -8.55kcal/molepH: 7.4 T: 2°CAssay Description:A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM202460(US9540357, example 32 | US9540357, example 33)
Affinity DataKi:  4.83E+3nM ΔG°:  -7.25kcal/molepH: 7.4 T: 2°CAssay Description:A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM202460(US9540357, example 32 | US9540357, example 33)
Affinity DataKi: >1.00E+4nM ΔG°: >-6.82kcal/molepH: 7.4 T: 2°CAssay Description:A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM202460(US9540357, example 32 | US9540357, example 33)
Affinity DataKi: >1.00E+4nM ΔG°: >-6.82kcal/molepH: 7.4 T: 2°CAssay Description:A 384-well drug plate was prepared to contain 6 test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent