BDBM204118 US9539260, I3::US9763952, Example I3

SMILES Cc1cc(cnc1S(C)(=O)=O)N1CCOc2ccc(O[C@H]3CCN(C3)C(=O)C3CCOCC3)c(F)c12

InChI Key InChIKey=FBABWYHCUSCASZ-IBGZPJMESA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 204118   

LigandPNGBDBM204118(US9539260, I3 | US9763952, Example I3)
Affinity DataIC50:  836nMT: 2°CAssay Description:Determination of Enzymatic PI3K Alpha and PI3K Delta Isoform Inhibition1.1 Test of Lipid Kinase ActivityThe efficacy of the compounds of examples 1-1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM204118(US9539260, I3 | US9763952, Example I3)
Affinity DataIC50:  6nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM204118(US9539260, I3 | US9763952, Example I3)
Affinity DataIC50:  836nMAssay Description:The kinase reaction is performed in a final volume of 50 μl per well of a half area COSTAR, 96 well plate. The final concentrations of ATP and p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM204118(US9539260, I3 | US9763952, Example I3)
Affinity DataIC50:  6nMT: 2°CAssay Description:Determination of Enzymatic PI3K Alpha and PI3K Delta Isoform Inhibition1.1 Test of Lipid Kinase ActivityThe efficacy of the compounds of examples 1-1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent