BDBM20460 (9Z)-N-[(4-hydroxy-3-methoxyphenyl)methyl]octadec-9-enamide::(Z)-N-[(4-hydroxy-3-methoxyphenyl)methyl]octadec-9-enamide::CHEMBL76903::N-Vannilyloleoylamide::Olvanil

SMILES CCCCCCCC\C=C/CCCCCCCC(=O)NCc1ccc(O)c(OC)c1

InChI Key InChIKey=OPZKBPQVWDSATI-KHPPLWFESA-N

Data  1 KI  2 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 20460   

TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20460((9Z)-N-[(4-hydroxy-3-methoxyphenyl)methyl]octadec-...)
Affinity DataKi:  1.59E+3nM ΔG°:  -7.91kcal/mole EC50:  132nMpH: 7.4 T: 2°CAssay Description:The hTRPV1-expressing CHO cell membranes were incubated with [3H]A-778317 and test compounds to establish equilibrium. After incubation was terminate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1/2/4(Rattus norvegicus)
Sandoz Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM20460((9Z)-N-[(4-hydroxy-3-methoxyphenyl)methyl]octadec-...)
Affinity DataEC50:  170nMAssay Description:Compound tested in vitro for [Ca2+] influx into neonatal rat dorsal root ganglia (DRG)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 2(Rattus norvegicus)
National Research Council (Cnr)

Curated by ChEMBL
LigandPNGBDBM20460((9Z)-N-[(4-hydroxy-3-methoxyphenyl)methyl]octadec-...)
Affinity DataIC50:  160nMAssay Description:Antagonist activity at recombinant rat TRPV2 expressed in HEK293 cells assessed as inhibition of LPC-induced Ca2+ levels preincubated for 5 mins foll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20460((9Z)-N-[(4-hydroxy-3-methoxyphenyl)methyl]octadec-...)
Affinity DataEC50:  0.501nMAssay Description:Concentration necessary to induce a relative half-maximal response measured by the entry of [Ca2+] into human embryonic kidney HEK293 cells overexpre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1/2/4(Rattus norvegicus)
Sandoz Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM20460((9Z)-N-[(4-hydroxy-3-methoxyphenyl)methyl]octadec-...)
Affinity DataEC50:  170nMAssay Description:In vitro effective concentration for Ca++ uptake into dorsal root ganglia neurones in cultureMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 2(Rattus norvegicus)
National Research Council (Cnr)

Curated by ChEMBL
LigandPNGBDBM20460((9Z)-N-[(4-hydroxy-3-methoxyphenyl)methyl]octadec-...)
Affinity DataIC50:  1.70E+3nMAssay Description:Antagonist activity at recombinant rat TRPV2 expressed in HEK293 cells assessed as inhibition of CBD-induced Ca2+ levels preincubated for 5 mins foll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed