BDBM204712 US9243002, 52::US9243002, 53::US9243002, 54

SMILES CNC(=O)c1c(oc2cc(N(C)S(C)(=O)=O)c(cc12)-c1ccc2CC(CO)n3c(cc4c(F)cccc34)-c2n1)-c1ccc(F)cc1

InChI Key InChIKey=NWORADADRBBBRF-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 204712   

TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM204712(US9243002, 52 | US9243002, 53 | US9243002, 54)
Affinity DataIC50:  3.35nMAssay Description:To initiate an assay, replicon cells were plated in the presence of a dilution series of test compound in the absence of G418. Typically, the assays ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM204712(US9243002, 52 | US9243002, 53 | US9243002, 54)
Affinity DataIC50:  8.07nMAssay Description:To initiate an assay, replicon cells were plated in the presence of a dilution series of test compound in the absence of G418. Typically, the assays ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM204712(US9243002, 52 | US9243002, 53 | US9243002, 54)
Affinity DataIC50:  2.25nMAssay Description:To initiate an assay, replicon cells were plated in the presence of a dilution series of test compound in the absence of G418. Typically, the assays ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM204712(US9243002, 52 | US9243002, 53 | US9243002, 54)
Affinity DataIC50:  2.32nMAssay Description:To initiate an assay, replicon cells were plated in the presence of a dilution series of test compound in the absence of G418. Typically, the assays ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM204712(US9243002, 52 | US9243002, 53 | US9243002, 54)
Affinity DataIC50:  4.03nMAssay Description:To initiate an assay, replicon cells were plated in the presence of a dilution series of test compound in the absence of G418. Typically, the assays ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM204712(US9243002, 52 | US9243002, 53 | US9243002, 54)
Affinity DataIC50:  1.56nMAssay Description:To initiate an assay, replicon cells were plated in the presence of a dilution series of test compound in the absence of G418. Typically, the assays ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent