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BDBM204923 phosphonoacetohydroxamate (PhAH)

SMILES: ONC(=O)CP(O)(O)=O

InChI Key: InChIKey=LDKRAXXVBWHMRH-UHFFFAOYSA-N

Data: 2 IC50

PDB links: 6 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 204923   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
hENO2 human recombinant Enolase


(Homo sapiens (Human))
BDBM204923
PNG
(phosphonoacetohydroxamate (PhAH))
Show SMILES ONC(=O)CP(O)(O)=O
Show InChI InChI=1S/C2H6NO5P/c4-2(3-5)1-9(6,7)8/h5H,1H2,(H,3,4)(H2,6,7,8)
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

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DrugBank
PC cid
PC sid
PDB
UniChem
PDB
Article
PubMed
n/an/a 62.3n/an/an/an/an/an/a



University of Texas MD Anderson Cancer Center



Assay Description
Enolase activity was measured by two different methods: a fluorometric NADH-linked assay or adirect spectrophotometric assay via formation of PEP. In...


Nat Chem Biol 12: 1053-1058 (2016)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Enolase 1 (ENO1)


(Homo sapiens (Human))
BDBM204923
PNG
(phosphonoacetohydroxamate (PhAH))
Show SMILES ONC(=O)CP(O)(O)=O
Show InChI InChI=1S/C2H6NO5P/c4-2(3-5)1-9(6,7)8/h5H,1H2,(H,3,4)(H2,6,7,8)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

DrugBank
PC cid
PC sid
PDB
UniChem
Article
PubMed
n/an/a 53.2n/an/an/an/an/an/a



University of Texas MD Anderson Cancer Center



Assay Description
Enolase activity was measured by two different methods: a fluorometric NADH-linked assay or adirect spectrophotometric assay via formation of PEP. In...


Nat Chem Biol 12: 1053-1058 (2016)

More data for this
Ligand-Target Pair