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BDBM204924 SF2312

SMILES: O[C@H]1C[C@@H](C(=O)N1O)P(O)(O)=O

InChI Key: InChIKey=CGWBGDOPBYWJKZ-HRFVKAFMSA-N

Data: 2 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 204924   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
hENO2 human recombinant Enolase


(Homo sapiens (Human))
BDBM204924
PNG
(SF2312)
Show SMILES O[C@H]1C[C@@H](C(=O)N1O)P(O)(O)=O
Show InChI InChI=1S/C4H8NO6P/c6-3-1-2(12(9,10)11)4(7)5(3)8/h2-3,6,8H,1H2,(H2,9,10,11)/t2-,3-/m0/s1
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
PDB
UniChem
PDB
Article
PubMed
n/an/a 42.5n/an/an/an/an/an/a



University of Texas MD Anderson Cancer Center



Assay Description
Enolase activity was measured by two different methods: a fluorometric NADH-linked assay or adirect spectrophotometric assay via formation of PEP. In...


Nat Chem Biol 12: 1053-1058 (2016)


Article DOI: 10.1038/nchembio.2195
BindingDB Entry DOI: 10.7270/Q28W3C33
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Enolase 1 (ENO1)


(Homo sapiens (Human))
BDBM204924
PNG
(SF2312)
Show SMILES O[C@H]1C[C@@H](C(=O)N1O)P(O)(O)=O
Show InChI InChI=1S/C4H8NO6P/c6-3-1-2(12(9,10)11)4(7)5(3)8/h2-3,6,8H,1H2,(H2,9,10,11)/t2-,3-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
PDB
UniChem
Article
PubMed
n/an/a 37.9n/an/an/an/an/an/a



University of Texas MD Anderson Cancer Center



Assay Description
Enolase activity was measured by two different methods: a fluorometric NADH-linked assay or adirect spectrophotometric assay via formation of PEP. In...


Nat Chem Biol 12: 1053-1058 (2016)


Article DOI: 10.1038/nchembio.2195
BindingDB Entry DOI: 10.7270/Q28W3C33
More data for this
Ligand-Target Pair