BDBM204977 US9249085, I(ak)::US9624159, Compound I(ak)

SMILES Cc1cc(cc(CNc2c(C)ccc(OCC(O)=O)c2C)c1C)-c1cccc(F)c1

InChI Key InChIKey=JDRDZBXKNDKRIF-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 204977   

TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Fovea Pharmaceuticals

US Patent
LigandPNGBDBM204977(US9249085, I(ak) | US9624159, Compound I(ak))
Affinity DataEC50:  2nMAssay Description:Human CHO cells expressing the recombinant human prostanoid EP2 receptor were suspended in assay medium (HBSS buffer (Invitrogen) containing 20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM204977(US9249085, I(ak) | US9624159, Compound I(ak))
Affinity DataIC50: >300nMAssay Description:Cell membrane homogenate from Human embryonic kidney HEK-293(T) cells expressing recombinant human prostanoid EP4 receptor was used to perform Prosta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM204977(US9249085, I(ak) | US9624159, Compound I(ak))
Affinity DataIC50: >300nMpH: 6.0Assay Description:The competition reaction was initiated by incubation of membrane protein homogenate (20 μg protein) for 120 min at 22° C. with 0.5 nM [3H]PGE2 l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent