BDBM20531 N-{6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl}quinolin-7-amine::Pyrimidine derivative, 79

SMILES FC(F)(F)c1ccc(cc1)-c1cc(Nc2ccc3cccnc3c2)ncn1

InChI Key InChIKey=BFZXCGOWJMWJHM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 20531   

LigandPNGBDBM20531(N-{6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl}qui...)
Affinity DataIC50:  4.5nMpH: 7.4 T: 2°CAssay Description:TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM20531(N-{6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl}qui...)
Affinity DataIC50:  0.300nMAssay Description:TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM20531(N-{6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl}qui...)
Affinity DataIC50:  6.60nMAssay Description:TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM20531(N-{6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl}qui...)
Affinity DataIC50:  0.600nMpH: 7.4 T: 2°CAssay Description:TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed