BDBM205334 US9249125, 87

SMILES Cc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(nn4-c4ccc(=O)n(CCO)c4)C(C)(C)C)c4ccccc34)n2)cc2cn[nH]c12

InChI Key InChIKey=ZFAJIINWCGZNAM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 205334   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
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US Patent
LigandPNGBDBM205334(US9249125, 87)
Affinity DataIC50:  45nMAssay Description:The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
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US Patent
LigandPNGBDBM205334(US9249125, 87)
Affinity DataIC50:  1.10E+3nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
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US Patent
LigandPNGBDBM205334(US9249125, 87)
Affinity DataIC50:  4nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
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US Patent
LigandPNGBDBM205334(US9249125, 87)
Affinity DataIC50:  2nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent