BDBM20668 ethyl N-(4-methyl-3-{[5-methyl-6-(propylcarbamoyl)pyrrolo[1,2-a][1,2,4]triazin-4-yl]amino}phenyl)carbamate::pyrrolo[2,1-f][1,2,4]triazine analogue, 21b

SMILES CCCNC(=O)c1cn2ncnc(Nc3cc(NC(=O)OCC)ccc3C)c2c1C

InChI Key InChIKey=MHSSSOPSKCOGJV-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20668   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM20668(ethyl N-(4-methyl-3-{[5-methyl-6-(propylcarbamoyl)...)
Affinity DataIC50:  5.5nM EC50:  69nMpH: 7.5 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed