BDBM206774 (S,S)- 4::US9492405, (S,S)-4

SMILES C[C@@H](Cc1cccc(N)c1)NC[C@@H](O)c1cc(O)cc(O)c1

InChI Key InChIKey=YSDUJIGQJOLYND-APPDUMDISA-N

Data  2 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 206774   

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services

US Patent
LigandPNGBDBM206774((S,S)- 4 | US9492405, (S,S)-4)
Affinity DataKi:  2.87E+4nM ΔG°:  -5.76kcal/molepH: 7.8 T: 2°CAssay Description:Beta1-AR binding was done on rat cortical membrane following a previously described procedure (Beer et al., Biochem. Pharmacol. 37: 1145-1151, 1988)....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services

US Patent
LigandPNGBDBM206774((S,S)- 4 | US9492405, (S,S)-4)
Affinity DataKi: >1.00E+5nM ΔG°: >-5.07kcal/molepH: 7.8 T: 2°CAssay Description:Beta1-AR binding was done on rat cortical membrane following a previously described procedure (Beer et al., Biochem. Pharmacol. 37: 1145-1151, 1988)....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services

US Patent
LigandPNGBDBM206774((S,S)- 4 | US9492405, (S,S)-4)
Affinity DataKd:  2.88E+4nMpH: 7.7Assay Description:HEK 293 cells stability transfected with cDNA encoding human beta2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent