BDBM20719 (1R,2R)-2-({4-[4-({[3-(trifluoromethyl)phenyl]carbamoyl}amino)phenyl]phenyl}carbonyl)cyclopentane-1-carboxylic acid::Urea-based Analogue, 4c

SMILES OC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(cc1)-c1ccc(NC(=O)Nc2cccc(c2)C(F)(F)F)cc1

InChI Key InChIKey=OMVIMIJGNZGGRI-DHIUTWEWSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 20719   

TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Abbott Laboratories

LigandPNGBDBM20719((1R,2R)-2-({4-[4-({[3-(trifluoromethyl)phenyl]carb...)
Affinity DataIC50:  17nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20719((1R,2R)-2-({4-[4-({[3-(trifluoromethyl)phenyl]carb...)
Affinity DataIC50:  10nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed