BDBM207841 US9266828, D

SMILES [#6]-[#6](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#7]-[#6](-[#7])=[#7])-[#7]-[#6](-[#6])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccc(cc1)\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6]-c1ccc(cc1)-[#6](\[#7])=[#7]\[#8]

InChI Key InChIKey=CNIHKEDRWBNIMO-SDHOMARFSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 207841   

TargetFurin(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM207841(US9266828, D)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of human furin using Pyr-RTKR-AMC as substrate preincubated for 30 mins followed by substrate addition and measured by fluorescence based ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFurin(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM207841(US9266828, D)
Affinity DataIC50:  1.20E+3nMpH: 7.5 T: 2°CAssay Description:Furin activity was measured in triplicate in wells of a 96-well plate in 0.2 ml 50 mM HEPES, pH 7.5, containing 1 mM CaCl2, 0.005% Brij-35 and 20% gl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent