BDBM208496 US9266870, 12::US9266870, 13

SMILES Fc1ccc(nc1)-c1ccn(CC2OCCN2C(=O)c2cc(F)ccc2-n2nccn2)n1

InChI Key InChIKey=LWIJBIHKOCBNNV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 208496   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM208496(US9266870, 12 | US9266870, 13)
Affinity DataIC50:  19.5nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM208496(US9266870, 12 | US9266870, 13)
Affinity DataIC50:  251nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM208496(US9266870, 12 | US9266870, 13)
Affinity DataIC50:  171nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM208496(US9266870, 12 | US9266870, 13)
Affinity DataIC50:  121nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent