BDBM208706 US9266876, 173

SMILES C[C@@H]1CN(CCN1C(=O)Cn1cccn1)c1sc(nc1-c1nc2ccccc2[nH]1)C(F)(F)F

InChI Key InChIKey=CRYXEDQPNCNOKN-CYBMUJFWSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 208706   

TargetC-X-C chemokine receptor type 3/Guanine nucleotide-binding protein subunit alpha-15(Homo sapiens (Human))
Actelion Pharmaceuticals

US Patent
LigandPNGBDBM208706(US9266876, 173)
Affinity DataIC50:  0.5nMpH: 7.4 T: 2°CAssay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM208706(US9266876, 173)
Affinity DataIC50:  191nMAssay Description:Antagonist activity at human recombinant CXCR3 in human venous blood assessed as receptor internalization measured for 30 mins in presence of CXCL10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM208706(US9266876, 173)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at human recombinant CXCR3 expressed in CHO-K1 cells measured after 10 mins in presence of CXCL10 by FLIPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed