BDBM208960 US9266881, 7-2
SMILES COc1ccc(CC(C)(O)c2cccc3nn(CCc4ccc5ccccc5n4)c(=O)n23)cc1
InChI Key InChIKey=ZZHRTAZEBDUIBK-UHFFFAOYSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 208960
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 11nM ΔG°: -10.8kcal/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAPĀ® FP kit supplied by Molecular Devices, Sunn...More data for this Ligand-Target Pair