BDBM209226 US9266877, 172

SMILES COCCOC1(Cn2c(C)c(cc2C#N)-c2ccc(nc2C(O)=O)N2CCc3cccc(C(=O)Nc4nc5ccccc5s4)c3C2)CCCCCC1

InChI Key InChIKey=ZSPPFPZZYXTXSZ-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 209226   

TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM209226(US9266877, 172)
Affinity DataKi: <0.100nM ΔG°: <-13.6kcal/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl-2-like protein 1(Mus musculus (Mouse))
Abbvie

US Patent
LigandPNGBDBM209226(US9266877, 172)
Affinity DataEC50:  1nMAssay Description:The efficacy of the compounds of Formula (I) can also be determined in cell-based killing assays using a variety of cell lines and mouse tumor models...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent