BDBM209856 US9273052, 15::US9566277, 15

SMILES FC(F)(F)c1nnc2CN(CCn12)C(=O)c1cccc(Cc2n[nH]c(=O)c3ccccc23)c1

InChI Key InChIKey=GFQHOURETBJHTJ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 209856   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical

US Patent
LigandPNGBDBM209856(US9273052, 15 | US9566277, 15)
Affinity DataIC50:  2.30nMT: 2°CAssay Description:The tested compounds were dissolved in dimethylsulfoxide and then diluted with 1x buffer to the concentration desired in the experiment. 25 uL of a 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical

US Patent
LigandPNGBDBM209856(US9273052, 15 | US9566277, 15)
Affinity DataEC50:  51nMAssay Description:Inhibition of PARP in human HeLa cells assessed as induction of centrosome declustering after 48 hrs by DAPI-staining based image analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Jiangsu Hansoh Pharmaceutical

US Patent
LigandPNGBDBM209856(US9273052, 15 | US9566277, 15)
Affinity DataIC50:  2.30nMT: 2°CAssay Description:he assay described below is to determine the activity of the compounds of the present invention for inhibiting the enzyme activity of PARP by using t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent