BDBM209856 US9273052, 15::US9566277, 15
SMILES FC(F)(F)c1nnc2CN(CCn12)C(=O)c1cccc(Cc2n[nH]c(=O)c3ccccc23)c1
InChI Key InChIKey=GFQHOURETBJHTJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 209856
Affinity DataIC50: 2.30nMT: 2°CAssay Description:The tested compounds were dissolved in dimethylsulfoxide and then diluted with 1x buffer to the concentration desired in the experiment. 25 uL of a 2...More data for this Ligand-Target Pair
Affinity DataEC50: 51nMAssay Description:Inhibition of PARP in human HeLa cells assessed as induction of centrosome declustering after 48 hrs by DAPI-staining based image analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMT: 2°CAssay Description:he assay described below is to determine the activity of the compounds of the present invention for inhibiting the enzyme activity of PARP by using t...More data for this Ligand-Target Pair