BDBM210425 US9546153, ex. 416

SMILES CC(C)(O)[C@H](F)CNC(=O)c1cnc(Nc2ccc3ncsc3c2)cc1Nc1ncc(CO)s1

InChI Key InChIKey=SMIJUOBDDWEMLM-GOSISDBHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 210425   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM210425(US9546153, ex. 416)
Affinity DataIC50:  1.80nMpH: 7.2 T: 2°CAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent