BDBM210947 2-(((1r,4r)-4-hydroxycyclohexyl)amino)-4-(2-(pyridin-3-yl)-1H-pyrrol-1-yl)benzamide (5i)::US10975030, Compound 5i

SMILES NC(=O)c1ccc(cc1NC1CCC(O)CC1)-n1cccc1-c1cccnc1

InChI Key InChIKey=DXVJSFNJKWFMNJ-UHFFFAOYSA-N

Data  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 210947   

TargetEndoplasmin(Homo sapiens (Human))
The University Of Kansas

LigandPNGBDBM210947(2-(((1r,4r)-4-hydroxycyclohexyl)amino)-4-(2-(pyrid...)
Affinity DataKd:  5.50E+3nMpH: 7.3Assay Description:Assay buffer (25 μL, 20 mM HEPES at pH 7.3, 50 mM KCl, 5 mM MgCl2, 1 mM DTT, 20 mM Na2MoO4, 0.01% NP-40, and 0.5 mg mL−1 BGG) was added to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
University Of Kansas

US Patent
LigandPNGBDBM210947(2-(((1r,4r)-4-hydroxycyclohexyl)amino)-4-(2-(pyrid...)
Affinity DataKd: >1.00E+5nMAssay Description:Assay buffer (25 μL, 20 mM HEPES pH 7.3, 50 mM KCl, 5 mM MgCl2, 1 mM DTT, 20 mM Na2MoO4, 0.01% NP-40, and 0.5 mg/mL BGG) was added to 96-well pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
University Of Kansas

US Patent
LigandPNGBDBM210947(2-(((1r,4r)-4-hydroxycyclohexyl)amino)-4-(2-(pyrid...)
Affinity DataKd: >1.00E+5nMpH: 7.3Assay Description:Assay buffer (25 μL, 20 mM HEPES at pH 7.3, 50 mM KCl, 5 mM MgCl2, 1 mM DTT, 20 mM Na2MoO4, 0.01% NP-40, and 0.5 mg mL−1 BGG) was added to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed