BDBM211880 US9290459, 45.1::US9670166, 45.1

SMILES FC(F)(F)c1cccc(c1)N1C2=C([C@H](N(C(=O)NCC#N)C1=O)c1ccc(cc1)C#N)C(=O)CC2

InChI Key InChIKey=WGIKYFBYLKLBRK-OAQYLSRUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 211880   

TargetNeutrophil elastase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM211880(US9290459, 45.1 | US9670166, 45.1)
Affinity DataIC50: <1nMpH: 7.5 T: 2°CAssay Description:Materials: Human neutrophil elastase was purchased from Calbiochem (Cat. No.: 324681) and the elastase substrate MeOSuc-Ala-Ala-Pro-Val-AMC from Bach...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM211880(US9290459, 45.1 | US9670166, 45.1)
Affinity DataIC50: <1nMpH: 7.5 T: 2°CAssay Description:Materials: Human neutrophil elastase was purchased from Calbiochem (Cat. No.: 324681) and the elastase substrate MeOSuc-Ala-Ala-Pro-Val-AMC from Bach...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent