BDBM2125 1-(5-bromopyridin-2-yl)-3-{2-[2,6-difluoro-3-(methoxymethyl)phenyl]ethyl}thiourea::LY300046HCl Analog 9::N-[2,6-Difluoro-3-(methoxymethyl)phenethyl]-N-[2-(5-bromopyridyl)]thiourea::PETT deriv.
SMILES COCc1ccc(F)c(CCNC(=S)Nc2ccc(Br)cn2)c1F
InChI Key InChIKey=NPVRMVYEJWRPDK-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 2125
Affinity DataIC50: 4nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Eli Lilly
Eli Lilly
Affinity DataIC50: 100nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1127,L687I]/[588-1147,L687I](Human immunodeficiency virus type 1)
Eli Lilly
Eli Lilly
Affinity DataIC50: 720nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair