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BDBM212756 US9556111, Table 1.22::US9951033, Compound Table 1.23

SMILES: CN(C)c1ccc(C[NH+](Cc2ccccc2)Cc2ccc(cc2)N(C)C)cc1

InChI Key: InChIKey=UNASQULGZIISMF-UHFFFAOYSA-O

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 212756   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
A-kinase anchor protein 7 isoform gamma (AKAP-18)


(Mus musculus (Mouse))
BDBM212756
PNG
(US9556111, Table 1.22 | US9951033, Compound Table ...)
Show SMILES CN(C)c1ccc(C[NH+](Cc2ccccc2)Cc2ccc(cc2)N(C)C)cc1
Show InChI InChI=1S/C25H31N3/c1-26(2)24-14-10-22(11-15-24)19-28(18-21-8-6-5-7-9-21)20-23-12-16-25(17-13-23)27(3)4/h5-17H,18-20H2,1-4H3/p+1
PDB

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 2.00E+3n/an/an/an/a



UNIVERSITETET I OSLO

US Patent


Assay Description
Stable and optimal assay conditions were determined by cross-titrating GST-AKAP18 δ and biotinylated PLB using 10 μg/ml glutathione accepto...


US Patent US9951033 (2018)

More data for this
Ligand-Target Pair
A-kinase anchor protein 7 isoform gamma


(Homo sapiens (Human))
BDBM212756
PNG
(US9556111, Table 1.22 | US9951033, Compound Table ...)
Show SMILES CN(C)c1ccc(C[NH+](Cc2ccccc2)Cc2ccc(cc2)N(C)C)cc1
Show InChI InChI=1S/C25H31N3/c1-26(2)24-14-10-22(11-15-24)19-28(18-21-8-6-5-7-9-21)20-23-12-16-25(17-13-23)27(3)4/h5-17H,18-20H2,1-4H3/p+1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 2.00E+3n/an/an/an/a



UNIVERSITETET I OSLO

US Patent


Assay Description
Stable and optimal assay conditions were determined by cross-titrating GST-AKAP18δ and biotinylated PLB using 10 μg/ml glutathione acceptor...


US Patent US9556111 (2017)


BindingDB Entry DOI: 10.7270/Q20Z758K
More data for this
Ligand-Target Pair