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BDBM212758 US9556111, Table 1.23

SMILES: Cc1ccc(NC(=O)Nc2ccc(CN(Cc3ccccc3)Cc3ccc(NC(=O)Nc4ccc(C)cc4)cc3)cc2)cc1

InChI Key: InChIKey=GDOGNDIWWBUHNX-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 212758   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
A-kinase anchor protein 7 isoform gamma


(Human)
BDBM212758
PNG
(US9556111, Table 1.23)
Show SMILES Cc1ccc(NC(=O)Nc2ccc(CN(Cc3ccccc3)Cc3ccc(NC(=O)Nc4ccc(C)cc4)cc3)cc2)cc1
Show InChI InChI=1S/C37H37N5O2/c1-27-8-16-32(17-9-27)38-36(43)40-34-20-12-30(13-21-34)25-42(24-29-6-4-3-5-7-29)26-31-14-22-35(23-15-31)41-37(44)39-33-18-10-28(2)11-19-33/h3-23H,24-26H2,1-2H3,(H2,38,40,43)(H2,39,41,44)
PDB

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PC cid
PC sid
UniChem
n/an/an/an/a 2.50E+3n/an/an/an/a



UNIVERSITETET I OSLO

US Patent


Assay Description
Stable and optimal assay conditions were determined by cross-titrating GST-AKAP18δ and biotinylated PLB using 10 μg/ml glutathione acceptor...


US Patent US9556111 (2017)

More data for this
Ligand-Target Pair