BDBM21439 N-Benylpiperazine derivative, 23g::N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)butan-2-yl]amino}-3-nitrobenzene)sulfonyl]-4-(4-{[2-(morpholin-4-yl)phenyl]methyl}piperazin-1-yl)benzamide

SMILES CN(C)CC[C@H](CSc1ccccc1)Nc1ccc(cc1[N+]([O-])=O)S(=O)(=O)NC(=O)c1ccc(cc1)N1CCN(Cc2ccccc2N2CCOCC2)CC1

InChI Key InChIKey=ATBNCVGFQYBJBN-MGBGTMOVSA-N

Data  2 KI  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 21439   

TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21439(N-Benylpiperazine derivative, 23g | N-[(4-{[(2R)-4...)
Affinity DataKi: <0.5nM IC50: <60nM EC50:  430nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21439(N-Benylpiperazine derivative, 23g | N-[(4-{[(2R)-4...)
Affinity DataKi: <1nM EC50:  460nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed