BDBM21506 Dihydropyrrolopyrazole, 15a::dimethyl[2-({4-[2-(pyridin-2-yl)-4H,5H,6H-pyrrolo[1,2-a]pyrazol-3-yl]quinolin-7-yl}oxy)ethyl]amine

SMILES CN(C)CCOc1ccc2c(ccnc2c1)-c1c2CCCn2nc1-c1ccccn1

InChI Key InChIKey=ZJSRFPPWMSAHCM-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 21506   

TargetTGF-beta receptor type-1 [4-503,T204D](Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM21506(Dihydropyrrolopyrazole, 15a | dimethyl[2-({4-[2-(p...)
Affinity DataIC50:  24nM EC50:  29nMpH: 7.5 T: 2°CAssay Description:The kinase activity was assayed by the autophosphorylation reaction of ALK5 (T204D) in the presence of 4 uM ATP and [33P]-gamma-ATP. After incubation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed