BDBM215094 US9296736, 45::US9593129, Example 45
SMILES OC(=O)C[C@@H]1CC([C@H](N(CC2CCCC2)C1=O)c1ccc(Cl)cc1)c1cccc(Cl)c1
InChI Key InChIKey=UQGIWBFVKAEKAL-ITPZNCDISA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 215094
Affinity DataIC50: 550nMAssay Description:The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in...More data for this Ligand-Target Pair
TargetCellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188](Homo sapiens (Human))
Amgen
US Patent
Amgen
US Patent
Affinity DataIC50: 550nMpH: 7.4 T: 2°CAssay Description:The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in...More data for this Ligand-Target Pair