BDBM21611 2-[(3S)-5-chloro-1'-[(5-chloro-2-fluorophenyl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,5'-dione]acetic acid::Spiro-indolinone analogue, (S)-90
SMILES OC(=O)CN1C(=O)[C@]2(CN(Cc3cc(Cl)ccc3F)C(=O)C2)c2cc(Cl)ccc12
InChI Key InChIKey=ABVCZPJCOYQLBK-HXUWFJFHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 21611
Affinity DataKi: 13nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in CHO cells after 90 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 88nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:Antagonist activity at CRTH2 receptor in human whole blood assessed as inhibition of PGD2-induced eosinophil chemotaxisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Antagonist activity at CRTH2 receptor in human whole blood assessed as inhibition of PGD2-induced eosinophil shape change pretreated for 20 mins meas...More data for this Ligand-Target Pair