BDBM21710 3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(propan-2-yl)-1,2-oxazol-4-yl]methoxy}phenyl)ethenyl]-N-propylbenzamide::Isoxazole derivative, 11a

SMILES CCCNC(=O)c1cccc(\C=C\c2ccc(OCc3c(noc3C(C)C)-c3c(Cl)cccc3Cl)cc2Cl)c1

InChI Key InChIKey=OOWVKBAYJHDSEH-VAWYXSNFSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 21710   

TargetBile acid receptor(Homo sapiens (Human))
University Of Tokyo

LigandPNGBDBM21710(3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...)
Affinity DataEC50:  9.00E+3nMpH: 7.2 T: 2°CAssay Description:Compounds were screened for agonist/antagonist activity on FXR-GAL4 chimeric receptors in transiently transfected HEK-293 cells. The EC50/IC50 values...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed