BDBM21776 2-[(1S)-5-{3-[2-chloro-4-(4H-1,2,4-triazol-4-yl)phenoxy]propoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid::Indanylacetic Acid Analog, 17w

SMILES OC(=O)C[C@@H]1CCc2cc(OCCCOc3ccc(cc3Cl)-n3cnnc3)ccc12

InChI Key InChIKey=SUBFPLVLQKUFIF-INIZCTEOSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 21776   

TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Bayer Healthcare Pharmaceuticals

LigandPNGBDBM21776(2-[(1S)-5-{3-[2-chloro-4-(4H-1,2,4-triazol-4-yl)ph...)
Affinity DataEC50:  6.85E+3nMpH: 7.4 T: 2°CAssay Description:Activity was assessed by measuring the human PPAR ligand binding domain with the co-activator protein. Europium labeled anti-GST antibody, streptavid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Bayer Healthcare Pharmaceuticals

LigandPNGBDBM21776(2-[(1S)-5-{3-[2-chloro-4-(4H-1,2,4-triazol-4-yl)ph...)
Affinity DataEC50:  2.23E+3nMT: 2°CAssay Description:Activity was assessed by measuring the human PPAR ligand binding domain with the co-activator protein. Europium labeled anti-GST antibody, streptavid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM21776(2-[(1S)-5-{3-[2-chloro-4-(4H-1,2,4-triazol-4-yl)ph...)
Affinity DataEC50:  1.17E+5nMAssay Description:Agonist activity at Homo sapiens (human) PPARgamma expressed in mouse 3T3-L1 cells incubated for 2 days followed by compound wash out measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Bayer Healthcare Pharmaceuticals

LigandPNGBDBM21776(2-[(1S)-5-{3-[2-chloro-4-(4H-1,2,4-triazol-4-yl)ph...)
Affinity DataEC50:  4.48E+5nMAssay Description:Agonist activity at GST-tagged Homo sapiens (human) PPARdelta ligand binding domain after 2 hr by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Bayer Healthcare Pharmaceuticals

LigandPNGBDBM21776(2-[(1S)-5-{3-[2-chloro-4-(4H-1,2,4-triazol-4-yl)ph...)
Affinity DataEC50:  1.46E+5nMAssay Description:Agonist activity at GST-tagged Homo sapiens (human) PPARalpha ligand binding domain after 2 hr by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
LigandPNGBDBM21776(2-[(1S)-5-{3-[2-chloro-4-(4H-1,2,4-triazol-4-yl)ph...)
Affinity DataEC50:  8.70E+3nMT: 2°CAssay Description:PPAR gamma activity was assessed by using the IRBA in mouse 3T3-L1 cells. This assay measures the ability of test compound to cause an increase in th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed