BDBM21800 2-[(1S)-5-{3-[4-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)phenoxy]propoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid::Indanylacetic Acid Analog, 34o

SMILES OC(=O)C[C@@H]1CCc2cc(OCCCOc3ccc(cc3)-c3nc4CCCCc4s3)ccc12

InChI Key InChIKey=NTVBAWSNQRKVKF-FQEVSTJZSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 21800   

TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Bayer Healthcare Pharmaceuticals

LigandPNGBDBM21800(2-[(1S)-5-{3-[4-(4,5,6,7-tetrahydro-1,3-benzothiaz...)
Affinity DataEC50:  391nMT: 2°CAssay Description:Activity was assessed by measuring the human PPAR ligand binding domain with the co-activator protein. Europium labeled anti-GST antibody, streptavid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Bayer Healthcare Pharmaceuticals

LigandPNGBDBM21800(2-[(1S)-5-{3-[4-(4,5,6,7-tetrahydro-1,3-benzothiaz...)
Affinity DataEC50:  2.20nMT: 2°CAssay Description:Activity was assessed by measuring the human PPAR ligand binding domain with the co-activator protein. Europium labeled anti-GST antibody, streptavid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM21800(2-[(1S)-5-{3-[4-(4,5,6,7-tetrahydro-1,3-benzothiaz...)
Affinity DataEC50:  3.47E+6nMAssay Description:Agonist activity at Homo sapiens (human) PPARgamma expressed in mouse 3T3-L1 cells incubated for 2 days followed by compound wash out measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Bayer Healthcare Pharmaceuticals

LigandPNGBDBM21800(2-[(1S)-5-{3-[4-(4,5,6,7-tetrahydro-1,3-benzothiaz...)
Affinity DataEC50:  4.55E+8nMAssay Description:Agonist activity at GST-tagged Homo sapiens (human) PPARdelta ligand binding domain after 2 hr by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Bayer Healthcare Pharmaceuticals

LigandPNGBDBM21800(2-[(1S)-5-{3-[4-(4,5,6,7-tetrahydro-1,3-benzothiaz...)
Affinity DataEC50:  2.56E+6nMAssay Description:Agonist activity at GST-tagged Homo sapiens (human) PPARalpha ligand binding domain after 2 hr by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM21800(2-[(1S)-5-{3-[4-(4,5,6,7-tetrahydro-1,3-benzothiaz...)
Affinity DataEC50:  294nMT: 2°CAssay Description:PPAR gamma activity was assessed by using the IRBA in mouse 3T3-L1 cells. This assay measures the ability of test compound to cause an increase in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed