BDBM218159 US9249087, 2

SMILES ONC(=O)c1ccc(Cn2ccc3ccccc23)cc1

InChI Key InChIKey=SUWMPMSWSJBENV-UHFFFAOYSA-N

Data  8 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 218159   

TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Illinois

US Patent
LigandPNGBDBM218159(US9249087, 2)
Affinity DataIC50:  5.83E+3nMpH: 8.0Assay Description:HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Illinois

US Patent
LigandPNGBDBM218159(US9249087, 2)
Affinity DataIC50:  9.19E+3nMpH: 8.0Assay Description:HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Illinois

US Patent
LigandPNGBDBM218159(US9249087, 2)
Affinity DataIC50:  9.75nMpH: 8.0Assay Description:HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Illinois

US Patent
LigandPNGBDBM218159(US9249087, 2)
Affinity DataIC50:  63nMAssay Description:Inhibition of dye-labeled tracer binding to HDAC6 (unknown origin) transfected in human HeLa cells measured after 2 hrs by nano-luciferase reporter g...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
University Of Illinois

US Patent
LigandPNGBDBM218159(US9249087, 2)
Affinity DataIC50:  8.16E+3nMpH: 8.0Assay Description:HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
European Molecular Biology Laboratory

Curated by ChEMBL
LigandPNGBDBM218159(US9249087, 2)
Affinity DataIC50:  63nMAssay Description:Inhibition of tubastatin-Alexa647-tracer binding to recombinant GST-tagged HDAC10 (unknown origin) measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
European Molecular Biology Laboratory

Curated by ChEMBL
LigandPNGBDBM218159(US9249087, 2)
Affinity DataIC50:  158nMAssay Description:Inhibition of dye-labeled tracer binding to HDAC10 (unknown origin) transfected in human HeLa cells measured after 2 hrs by nano-luciferase reporter ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University Of Illinois

US Patent
LigandPNGBDBM218159(US9249087, 2)
Affinity DataIC50:  417nMpH: 8.0Assay Description:HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent