BDBM21877 2,9-disubstituted 6-oxopurine, 12a::9-[4-(dimethylamino)butyl]-2-(phenylamino)-6,9-dihydro-3H-purin-6-one dihydrochloride::CHEMBL441732

SMILES CN(C)CCCCn1cnc2c1nc(Nc1ccccc1)[nH]c2=O

InChI Key InChIKey=HTDSDCIJZUTHGR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 21877   

TargetThymidine kinase(Human herpesvirus 1)
Glsynthesis

LigandPNGBDBM21877(2,9-disubstituted 6-oxopurine, 12a | 9-[4-(dimethy...)
Affinity DataIC50:  3.60E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Macacine herpesvirus 1)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM21877(2,9-disubstituted 6-oxopurine, 12a | 9-[4-(dimethy...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of Herpes B virus recombinant thymidine kinase-mediated [3H]TdR phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 2)
Glsynthesis

LigandPNGBDBM21877(2,9-disubstituted 6-oxopurine, 12a | 9-[4-(dimethy...)
Affinity DataIC50:  620nMAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed