BDBM218915 US9303033, A8, Table 22A, Compound 21::US9303033, V3, Table 13A, Compound 4

SMILES OCc1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1

InChI Key InChIKey=XDJDNFVTLAZCED-APSNUPSMSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 218915   

TargetCasein kinase II subunit alpha/beta(Homo sapiens (Human))
Senhwa Biosciences

US Patent
LigandPNGBDBM218915(US9303033, A8, Table 22A, Compound 21 | US9303033,...)
Affinity DataIC50: <10nMpH: 7.2Assay Description:In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase II subunit beta(Homo sapiens (Human))
Senhwa Biosciences

US Patent
LigandPNGBDBM218915(US9303033, A8, Table 22A, Compound 21 | US9303033,...)
Affinity DataIC50:  1.25E+3nMpH: 7.0Assay Description:5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5× Reaction Buffer (40 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase II subunit beta(Homo sapiens (Human))
Senhwa Biosciences

US Patent
LigandPNGBDBM218915(US9303033, A8, Table 22A, Compound 21 | US9303033,...)
Affinity DataIC50:  649nMpH: 7.0Assay Description:5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5× Reaction Buffer (40 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase II subunit alpha/beta(Homo sapiens (Human))
Senhwa Biosciences

US Patent
LigandPNGBDBM218915(US9303033, A8, Table 22A, Compound 21 | US9303033,...)
Affinity DataIC50: <10nMpH: 7.2Assay Description:In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent