BDBM219674 US9303033, K33, Table 37A, Compound 348

SMILES O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3ccccc3-n3cncn3)nc12

InChI Key InChIKey=HPTLSRIAYRXPJF-CHHVJCJISA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 219674   

TargetCasein kinase II subunit beta(Homo sapiens (Human))
Senhwa Biosciences

US Patent
LigandPNGBDBM219674(US9303033, K33, Table 37A, Compound 348)
Affinity DataIC50: >1.00E+3nMpH: 7.0Assay Description:Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5× Reaction Buffer (40 mM MOPS pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase II subunit alpha/beta(Homo sapiens (Human))
Senhwa Biosciences

US Patent
LigandPNGBDBM219674(US9303033, K33, Table 37A, Compound 348)
Affinity DataIC50: <10nMpH: 7.2Assay Description:In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent