BDBM22013 5-{[(1R,3S)-3-hydroxycyclopentane]sulfonyl}-3-methyl-1-(2-methylpropyl)-6-{[2-(trifluoromethyl)phenyl]methyl}-1H,2H,3H,4H-thieno[2,3-d]pyrimidine-2,4-dione::Thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione, (rac)-20

SMILES CC(C)Cn1c2sc(Cc3ccccc3C(F)(F)F)c(c2c(=O)n(C)c1=O)S(=O)(=O)[C@@H]1CC[C@H](O)C1

InChI Key InChIKey=KLVPSHRCXIALKY-JKSUJKDBSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22013   

TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM22013(5-{[(1R,3S)-3-hydroxycyclopentane]sulfonyl}-3-meth...)
Affinity DataKi:  12nM ΔG°:  -10.7kcal/molepH: 7.8 T: 2°CAssay Description:Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed