BDBM22014 5-{[(3R)-3-hydroxypyrrolidine-1-]sulfonyl}-3-methyl-1-(2-methylpropyl)-6-{[2-(trifluoromethyl)phenyl]methyl}-1H,2H,3H,4H-thieno[2,3-d]pyrimidine-2,4-dione::Thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione, (rac)-21

SMILES CC(C)Cn1c2sc(Cc3ccccc3C(F)(F)F)c(c2c(=O)n(C)c1=O)S(=O)(=O)N1CC[C@@H](O)C1

InChI Key InChIKey=QFJAWVIERUMTED-OAHLLOKOSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22014   

TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM22014(5-{[(3R)-3-hydroxypyrrolidine-1-]sulfonyl}-3-methy...)
Affinity DataKi:  1.10nM ΔG°:  -12.1kcal/molepH: 7.8 T: 2°CAssay Description:Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed