BDBM220555 US9296741, 144
SMILES CCS(=O)(=O)Nc1ccc(OCC(C)(C)C)c(c1)-c1cn(C)c(=O)c2[nH]ccc12
InChI Key InChIKey=MAEDJUGOIKDPTL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 220555
Affinity DataKi: 13.6nM ΔG°: -10.7kcal/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
Affinity DataKi: 17.8nM ΔG°: -10.6kcal/molepH: 6.0 T: 2°CAssay Description:A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...More data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:Binding affinity to human N-terminal His6-tagged BRD4 BD1-BD2 (K57 to K550 residues) after 1 hr using alexa-647 conjugated probe by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 79nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair