BDBM220833 US9296759, 98
SMILES COc1ccc(nc1)C(=O)Nc1ccc2Oc3c(F)nc(cc3C3(CCOC(N)=N3)c2c1)-c1ccnc(F)c1
InChI Key InChIKey=AYBGYGZHVQEVID-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 220833
Affinity DataIC50: 4.00E+5nMpH: 3.5Assay Description:Recombinant CathepsinD was expressed in CHO cells. The assay buffer for CathepsinD is 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The Cathepsi...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair