BDBM221070 SPHINX::US9695160, SPHINX::US9796707, Reference Compound SPHINX
SMILES Cc1ccc(o1)C(=O)Nc1cc(ccc1N1CCOCC1)C(F)(F)F
InChI Key InChIKey=FZCPNRVICXFZJR-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 221070
Affinity DataIC50: 880nMpH: 7.5 T: 2°CAssay Description:A reaction buffer containing 200 mM Tris pH 7.5, 100 mM MgCl2 and 0.1 mg/ml BSA was added to 43 μM SRSF1Arg-Ser (RS) peptide (NH2-RSPSYGRSRSRSRS...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:Inhibition of SRPK1 (unknown origin) using SRSF1 Arg-Ser (RS) peptide (NH2-RSPSYGRSRSRSRSRSRSRSRSNSRSRSY-OH) as substrate incubated for 10 mins in pr...More data for this Ligand-Target Pair
Affinity DataIC50: 440nMAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair
Affinity DataIC50: 440nMT: 2°CAssay Description:Candidate compounds were screened by the Kinase-Glo assay (Promega; Koresawa and Okabe, 2004), the results of which are shown in Table 1 and Table 2....More data for this Ligand-Target Pair