BDBM221071 SPHINX scaffold, 1

SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1ccc(C)o1)C(F)(F)F

InChI Key InChIKey=STWLHUZLPCVTAS-UHFFFAOYSA-N

Data  1 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 221071   

TargetSRSF protein kinase 1(Homo sapiens (Human))
Exonate

LigandPNGBDBM221071(SPHINX scaffold, 1)
Affinity DataIC50:  31nMpH: 7.5 T: 2°CAssay Description:A reaction buffer containing 200 mM Tris pH 7.5, 100 mM MgCl2 and 0.1 mg/ml BSA was added to 43 μM SRSF1Arg-Ser (RS) peptide (NH2-RSPSYGRSRSRSRS...More data for this Ligand-Target Pair